Nanofluidic Preconcentration Device for Sensitive and Wide Dynamic Range Immuno-sensing

نویسندگان

  • Ying-Chih Wang
  • Vincent H. Liu
  • Jongyoon Han
چکیده

This paper describes a microfluidic immunoassay device with integrated preconcentration system, enabling the detection of various analytes (proteins) at low target concentrations with faster binding kinetics. It not only complements recent advances of novel immuno-biosensors, but also can be used to further enhance the most novel and advanced immuno-biosensor systems developed. The work has demonstrated significant sensitivity/kinetics enhancement by the preconcentration of antigens before the binding.

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تاریخ انتشار 2007